c-mer proto-oncogene tyrosine kinase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_022943
Gene ID 65037
Unigene ID Rn.207207
Probe set ID -
Ensembl ID ENSRNOG00000017319

Orthologous Gene

Human[2]  NM_006343
Mouse[1]  NM_008587

Chromosomal Region

3q36  [116,308,387  -  116,416,414]

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

1299193
10699188
11592982
11861639
12912913
15130911
15180281
20238011
22871113

Gene Ontology  (GO ID)

Biological Process

GO:0043277  apoptotic cell clearance
GO:0001779  natural killer cell differentiation
GO:0051250  negative regulation of lymphocyte activation
GO:0006909  phagocytosis
GO:0030168  platelet activation
GO:0050766  positive regulation of phagocytosis
GO:0006468  protein amino acid phosphorylation
GO:0043491  protein kinase B signaling cascade
GO:0060041  retina development in camera-type eye
GO:0032940  secretion by cell
GO:0007283  spermatogenesis
GO:0034446  substrate adhesion-dependent cell spreading
GO:0060068  vagina development

Cellular Component

GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0001750  photoreceptor outer segment
GO:0016028  rhabdomere

Molecular Function

GO:0005524  ATP binding
GO:0004714  transmembrane receptor protein tyrosine kinase activity