B-cell CLL/lymphoma 3

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:113.90 ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001109422
Gene ID 680611
Unigene ID Rn.198135
Probe set ID -
Ensembl ID ENSRNOG00000043416

Orthologous Gene

Human[2]  NM_005178
Mouse[1]  NM_033601

Chromosomal Region

1q21  [79,122,801  -  79,137,035]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

20391111
21787835

Gene Ontology  (GO ID)

Biological Process

GO:0019730  antimicrobial humoral response
GO:0042742  defense response to bacterium
GO:0042832  defense response to protozoan
GO:0030330  DNA damage response, signal transduction by p53 class mediator
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0030198  extracellular matrix organization
GO:0002268  follicular dendritic cell differentiation
GO:0002467  germinal center formation
GO:0002455  humoral immune response mediated by circulating immunoglobulin
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0002315  marginal zone B cell differentiation
GO:0043066  negative regulation of apoptosis
GO:0045415  negative regulation of interleukin-8 biosynthetic process
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0042536  negative regulation of tumor necrosis factor biosynthetic process
GO:0032729  positive regulation of interferon-gamma production
GO:0045082  positive regulation of interleukin-10 biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0045727  positive regulation of translation
GO:0000060  protein import into nucleus, translocation
GO:0042981  regulation of apoptosis
GO:0051101  regulation of DNA binding
GO:0042345  regulation of NF-kappaB import into nucleus
GO:0006974  response to DNA damage stimulus
GO:0010225  response to UV-C
GO:0009615  response to virus
GO:0048536  spleen development
GO:0042088  T-helper 1 type immune response
GO:0045064  T-helper 2 cell differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0032996  Bcl3-Bcl10 complex
GO:0033257  Bcl3/NF-kappaB2 complex
GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0003677  DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding