similar to RT1 class II histocompatibility antigen, B-1 beta chain precursor (RT1.B-beta(1))

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.86 cerebellum:6.87 brain stem:7.02 corpus callosum/glia:- pineal gland:- peripheral nerve:6.57 spine:- retina:- eye:7.53 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:10.46 thymus:9.41 bone marrow:8.13 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.79 muscle:7.31 esophagus:- stomach:- intestine:8.73 colon:7.86 liver/hepato:- lung:- bladder:- kidney:7.72 pituitary:7.72 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001101017
Gene ID 688090
Unigene ID -
Probe set ID M36151cds_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000032708

Orthologous Gene

Human [0]  
Mouse[2]  NM_207105

Chromosomal Region

20p12  [4,730,560  -  4,736,186]

Gene Family (Interpro ID)

IPR014745  MHC class II, alpha/beta chain, N-terminal
IPR000353  MHC class II, beta chain, N-terminal
IPR011162  MHC classes I/II-like antigen recognition protein

Link to Pubmed  (Pubmed ID)

1904838
15517241

Gene Ontology  (GO ID)

Biological Process

GO:0019886  antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0002344  B cell affinity maturation
GO:0071346  cellular response to interferon-gamma
GO:0046635  positive regulation of alpha-beta T cell activation
GO:0002579  positive regulation of antigen processing and presentation
GO:0002827  positive regulation of T-helper 1 type immune response

Cellular Component

GO:0005769  early endosome
GO:0009897  external side of plasma membrane
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0042613  MHC class II protein complex
GO:0005771  multivesicular body

Molecular Function

GO:0042605  peptide antigen binding
GO:0015643  toxin binding
GO:0070491  transcription repressor binding
GO:0031625  ubiquitin protein ligase binding