cubilin (intrinsic factor-cobalamin receptor)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:- testis:82.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:319 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_053332
Gene ID 80848
Unigene ID Rn.3236
Probe set ID -
Ensembl ID ENSRNOG00000029047

Orthologous Gene

Human [0]  
Mouse[2]  NM_001081084

Chromosomal Region

17q12.3  [87,655,813  -  87,772,079]

Gene Family (Interpro ID)

IPR013091  EGF calcium-binding
IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

9153271
9478979
9691015
10080186
10400683
10811843
11581259
11595644
11805171
12724130
14576052
15286052
15578272
15616221
15976000
16027047
17037740
17442257
17453355
17990981
19202329
22337902

Gene Ontology  (GO ID)

Biological Process

GO:0008203  cholesterol metabolic process
GO:0020028  hemoglobin import
GO:0001701  in utero embryonic development
GO:0042953  lipoprotein transport
GO:0070207  protein homotrimerization
GO:0006898  receptor-mediated endocytosis
GO:0007584  response to nutrient
GO:0006766  vitamin metabolic process

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0005903  brush border
GO:0031526  brush border membrane
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0030139  endocytic vesicle
GO:0030666  endocytic vesicle membrane
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0010008  endosome membrane
GO:0005794  Golgi apparatus
GO:0043202  lysosomal lumen
GO:0005765  lysosomal membrane
GO:0016020  membrane
GO:0043234  protein complex

Molecular Function

GO:0005509  calcium ion binding
GO:0031419  cobalamin binding
GO:0030492  hemoglobin binding
GO:0042802  identical protein binding
GO:0042803  protein homodimerization activity
GO:0004872  receptor activity