sortilin 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:191.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:177.70 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:245.80 bone marrow:- adipose:294.40 bone:39 skin:-
GeneChip cerebrum:6.31 cerebellum:6.35 brain stem:6.40 corpus callosum/glia:- pineal gland:- peripheral nerve:6.65 spine:- retina:- eye:6.02 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.90 thymus:5.92 bone marrow:6.17 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:265.70 ovary:- testis:164.70 heart:193.90 muscle:- esophagus:- stomach:- intestine:209.30 colon:-     liver/hepato:-        lung:152    bladder:- kidney:- pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.85 muscle:5.92 esophagus:- stomach:- intestine:5.85 colon:5.92 liver/hepato:- lung:- bladder:- kidney:5.70 pituitary:5.85 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_031767
Gene ID 83576
Unigene ID Rn.11286
Probe set ID AF023621_at  [RG_U34A]
Ensembl ID ENSRNOG00000031814

Orthologous Gene

Human[4]  NM_001205228, NM_002959
Mouse[3]  NM_019972, NM_002959

Chromosomal Region

2q34  [203,853,009  -  203,931,559]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9305862
9452485
12746864
12771154
15057822
15987945
17997040
18090258
19429059
20083190
21261755
21730062

Gene Ontology  (GO ID)

Biological Process

GO:0006897  endocytosis
GO:0008333  endosome to lysosome transport
GO:0032509  endosome transport via multivesicular body sorting pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0046323  glucose import
GO:0006895  Golgi to endosome transport
GO:0008625  induction of apoptosis via death domain receptors
GO:0006886  intracellular protein transport
GO:0014902  myotube differentiation
GO:0043066  negative regulation of apoptosis
GO:0051005  negative regulation of lipoprotein lipase activity
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007218  neuropeptide signaling pathway
GO:0001503  ossification
GO:0048227  plasma membrane to endosome transport
GO:0010468  regulation of gene expression
GO:0032868  response to insulin stimulus
GO:0016050  vesicle organization

Cellular Component

GO:0043025  cell soma
GO:0009986  cell surface
GO:0030136  clathrin-coated vesicle
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0030425  dendrite
GO:0005769  early endosome
GO:0005789  endoplasmic reticulum membrane
GO:0010008  endosome membrane
GO:0005794  Golgi apparatus
GO:0032580  Golgi cisterna membrane
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0005765  lysosomal membrane
GO:0031965  nuclear membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0030140  trans-Golgi network transport vesicle

Molecular Function

GO:0019899  enzyme binding
GO:0048406  nerve growth factor binding
GO:0010465  nerve growth factor receptor activity
GO:0016492  neurotensin receptor activity, G-protein coupled
GO:0030379  neurotensin receptor activity, non-G-protein coupled