recombination activating gene 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:983.30 bone marrow:- adipose:- bone:39 skin:-
GeneChip cerebrum:4.91 cerebellum:5.07 brain stem:5.11 corpus callosum/glia:- pineal gland:- peripheral nerve:4.97 spine:- retina:- eye:4.74 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:4.71 thymus:5.51 bone marrow:5.13 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:4.97 muscle:4.92 esophagus:- stomach:- intestine:4.19 colon:4.43 liver/hepato:- lung:- bladder:- kidney:4.92 pituitary:4.67 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_053468
Gene ID 84600
Unigene ID Rn.92344
Probe set ID AJ006070_at  [RG_U34A]
Ensembl ID ENSRNOG00000004630

Orthologous Gene

Human[2]  NM_000448
Mouse[1]  NM_009019

Chromosomal Region

3q31  [86,780,782  -  86,791,878]

Gene Family (Interpro ID)

IPR018957  Zinc finger, C3HC4 RING-type
IPR013083  Zinc finger, RING/FYVE/PHD-type
IPR003604  Zinc finger, U1-type

Link to Pubmed  (Pubmed ID)

8810255
9630231
11214319
11859104
15371245
15522792
16929832
22964459
23364523

Gene Ontology  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0030183  B cell differentiation
GO:0016265  death
GO:0006310  DNA recombination
GO:0010390  histone monoubiquitination
GO:0043154  negative regulation of caspase activity
GO:0070233  negative regulation of T cell apoptosis
GO:0070244  negative regulation of thymocyte apoptosis
GO:0002331  pre-B cell allelic exclusion
GO:0051865  protein autoubiquitination
GO:0045580  regulation of T cell differentiation
GO:0033077  T cell differentiation in the thymus
GO:0043029  T cell homeostasis
GO:0048538  thymus development
GO:0033151  V(D)J recombination

Cellular Component

GO:0005575  cellular_component
GO:0005634  nucleus

Molecular Function

GO:0004519  endonuclease activity
GO:0042393  histone binding
GO:0046872  metal ion binding
GO:0003674  molecular_function
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding